Settings is the place where all configurations are saved for the product. It may be user specific or group specific or feature specific or UI specific. This has a set of links to navigate. Different options are enabled for different admins and users.
Users and Groups, System defined fields, User defined fields, Project Management, SMTP server settings are enabled for eadmin.
Activity Type, Host details, Lookup code, Defect Cycle are enabled for Project Admin.
Change Password, TimeZone, Default Project are enabled for all users.Use menus on the left hand side of this page to see the help of various settings options.